Understanding Spinal Cord Injury and Functional Goals & Outcomes

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Spinal Cord Injury - InfoSheet #5
Level - Advanced
Date: Updated July, 2000

Understanding the physiological effects of a spinal cord injury requires a basic knowledge of the anatomy and physiology of the spinal cord. Knowledge of the pathologic anatomy and physiology of a spinal cord injury (SCI) is also needed. Following this brief summary is a list of additional resources.

Anatomy and Physiology
The spinal cord is the largest nerve in the body. Nerves are cord-like structures made up of nerve fibers. Nerve fibers are responsible for the communication systems of the body, which include sensory, motor, and autonomic functions. The nerve fibers within the spinal cord carry messages between the brain and the rest of the body. Because the spinal cord is such an important part of the nervous system, protective bone segments, called the vertebral column, surround it. [[See Figure A] ]

The nerves that lie within the spinal cord are upper motor neurons (UMNs). They carry the messages back and forth from the brain to the spinal nerves along the spinal tract. The spinal nerves that branch out from the spinal cord to the other parts of the body are lower motor neurons (LMNs). These spinal nerves exit and enter at each vertebral level and communicate with specific areas of the body. The sensory portion of the LMNs carry messages to the brain about sensation from the skin and other body parts and organs. The motor portion of the LMNs send messages from the brain to the various body parts to initiate actions such as muscle movement. [See Figure C]

The vertebral column, or spinal column, is made up of 4 regions. Seven cervical vertebrae protect the eight cervical nerves; twelve thoracic vertebrae protect the twelve thoracic nerves; five lumbar vertebrae protect the five lumbar nerves; five sacral vertebrae, which are fused as one bone, help protect the five sacral nerves. [See Figure B] As the body grows, the vertebral column grows more in length than the spinal cord, which usually ends between the first and second lumbar vertebrae. From this point the lumbar and sacral nerves branch out from the spinal cord and descend inside the spinal column before leaving the vertebral column at their corresponding vertebrae. Because of this fact there is often a discrepancy between the skeletal or bony level of vertebral fracture and the neurological level of spinal cord injury. [See Figure B]

What Happens after A Spinal Cord Injury?
The term spinal cord injury (SCI) refers to any injury of the neural (pertaining to nerves) elements within the spinal canal. SCI can occur from either trauma or disease to the vertebral column or the spinal cord itself. Most spinal cord injuries are the result of trauma to the vertebral column. Such trauma can cause a fracture of bone or tearing of ligaments with displacement of the bony column. This causes a pinching of the spinal cord. The vertebral trauma may cause contusion with hemorrhage and swelling of the spinal cord or it may cause a tearing of the spinal cord and/or its nerve roots. The damage from the spinal cord injury can affect the nerve fibers sending and receiving of messages from the brain to the body's systems that control sensory, motor, and autonomic function below the level of injury. It is important to distinguish between injuries that occur in the spinal cord proper from those that occur to the conus medullaris or to the cauda equina. [See Figure B] A spinal cord injury with preservation of segments of spinal cord below the level of injury usually produces an upper moter neuron (UMN) type of injury or spastic paralysis. The intrinsic reflexes are now uninhibited and become hyperreflexic and lead to increased muscle tone, spasms, and spasticity. A conus medullaris injury, without preservation of spinal cord segments below the lesion, or a cauda equina injury produces a lower motor neuron (LMN) type of injury or flaccid paralysis. With this type of injury, the stimuli cannot reach the spinal cord; therefore, the reflexes and muscle tone remain decreased or absent (flaccid).
Classification
A complete evaluation of both sensory and motor levels will determine the neurological level of spinal cord injury. The recommended neurological assessment follows the classifications published in the "International Standards for Neurological and Functional Classification of Spinal Cord Injury", revised 1996, endorsed by the American Spinal Injury Association and the International Medical Society of Paraplegia. Radiologic or anatomical abnormalities are not used in this classification system.

Level of Injury
The neurologic level of injury is determined to be the most caudal (lowest) point on the spinal cord below which there is a decrease or absence of feeling (sensory level) and movement (motor level) on both sides of the body. The physician tests 10 paired groups of index muscles [myotomes] to determine the motor level of the patient. A motor score between 0 - 5 is given based on motor function. A "3" is given for active, full range of movement against gravity. This is the minimal score needed to set functional goals with a specific level of injury. The 28 key sensory points [dermatomes - the nerve roots that receive sensory information from the skin areas] are also examined for sensitivity to pin prick and light touch. This determines the sensory level. The sensory and motor levels need to be evaluated for both the right and left sides of the body. It is not unusual to have a discrepancy between the lowest normal motor level and the lowest normal sensory level.

Another general classification used to refer to a spinal cord injury are the terms tetraplegia or paraplegia. Tetraplegia [formerly called quadriplegia] generally describes the condition of a person classified with a spinal cord injury between C1 and T1. These individuals experience a loss of feeling and/or movement in their head, neck, shoulder, upper chest, arms, hands, and/or fingers. Paraplegia is the term that describes the condition of a person who has been classified with an injury between levels T2 and S5. The body's motor and/or sensory function(s) affected with paraplegia can include the middle of the chest, the stomach, hips, legs and feet, and/or toes.

Type of Injury
A complete injury means that there is no motor or sensory function preserved in the S4 and S5 area, or anal area. A rectal exam determines if there is rectal sensation and voluntary sphincteric contraction. If there is evidence of any motor or sensory function in this area, one of three incomplete injury classifications is given according to the ASIA Impairment Scale.
ASIA Impairment Scale
Type of Injury Description
A=Complete No motor or sensory function is preserved in the sacral segments S4-S5.
B=Incomplete Sensory but not motor function is preserved below the neurological level and includes the sacral segment S4-S5.
C=Incomplete Motor function is preserved below the neurological level, and more than half of key muscles below the neurological level have a muscle grade less than 3. Sensory function is present below the neurological level and includes sacral segments S4-S5.
D=Incomplete Motor function is preserved below the neurological level, and at least half of key muscles below the neurological level have a muscle grade of 3 or more. Sensory function is present below the neurological level and includes sacral segments S4-S5.
E=Normal Motor and sensory function is normal

Other Classifications
Also included in the neurological assessment is the classification of Clinical Syndromes. The syndromes include Central Cord, Brown-Sequard, Anterior Cord, Conus Medullaris, and Cauda Equina Syndrome. A mixed or unclassified syndrome is sometimes present.

A classification used in the evaluation process is the Functional Independence Measure (FIM). The FIM is a method for monitoring and evaluating progress associated with treatment. It measures daily life activities in the areas of self-care, sphincter control, mobility, locomotion, communication and social cognition. Activities such as eating, toileting, and dressing are rated on a scale which measures dependence/independence.

Functional Goals
Functional goals are a realistic expectation of activities that a person with spinal cord injury eventually should be able to do with a particular level of injury. These goals are set during rehabilitation by the individual with the assistance of the medical team. They help the individual with spinal cord injury learn new ways to manage his/her daily activities and stay healthy. Achievement of functional goals can also be affected by other factors, such as an individual's body type and health related issues. By striving to reach these functional goals, the hope is to give individuals with SCI the opportunity to achieve maximum independence.

The chart, "Functional Goals for Specific Levels of Complete Injury", shows the muscle and muscle activity tested and what functional goals can be expected for a person with a complete injury at a particular level. Motor and sensory functions improve with lower levels of injury.

Incidence [10]
Spinal cord injury occurs with an incidence of approximately 40 cases per million population in the U.S. or approximately 10,000 new cases each year. Spinal cord injury is primarily an injury of young men. The ratio of males to females is approximately 4 to 1 with 82% males and 18% females.

The greatest number of injuries occur between the ages of 16 and 30 (55%). The mean age at time of injury has increased from 28.6 in 1979 to 35.1 in 1990.

Since 1990, motor vehicle crashes account for 37.4% of the SCI cases reported. The next largest contributor is acts of violence (25.9%), primarily gunshot wounds. The third most common cause is falls at 21.5%, with sports injuries ranking fourth at 7.1%.

Spinal cord injury can occur at any level of the spinal column or at multiple levels. The most common area of injury is the lower part of the neck at the C-4, C-5, and C-6 levels. The second most common area is between T-12 and L-1, which is at the bottom of the rib cage. Since 1990 the most frequent neurologic category is incomplete tetraplegia (29.5%), followed by complete paraplegia (27.9%), incomplete paraplegia (21.3%), and complete tetraplegia (18.5%).

Individuals with a spinal cord injury designated as having tetraplegia are slightly more common than paraplegia, 51.7% and 46.7%, respectively.

References & Resources
  1. Consortium for Spinal Cord Medicine. Outcomes following traumatic spinal cord injury: Clinical practice guideleines for health-care professionals. 1999. [Available on www.pva.org/prof/9811cpgs/trauma.htm]
  2. Corbet, B, Spinal Network. 3rd Ed. Boulder, CO: Spinal Network, 1998:65-70. [Available from Spinal Network, PO Box 8987, Malibu, CA 90265-8987, 800-543-4116].
  3. Freed. MM. Traumatic and Congenital Lesions of the Spinal Cord. In: Kottke, FJ and Lehmann, JF Eds. Krusen's Handbook of Physical Medicine and Rehabilitation. 4th Ed. Philadelphia: Saunders Co, 1990; 717-748.
  4. Hammond M, Umlauf R, Matteson B, and Perduta-Fulginiti S. Yes, You Can! A Guide to Self-care for Persons with Spinal Cord Injury. 2nd Ed. Washington, DC: Paralyzed Veterans of America, 1993.
  5. International Standards for Neurological and Functional Classification of SCI, Rev. 1996. American Spinal Injury Association. [Available on www.asia-spinalinjury.org/publications/ASIAClass.html].
  6. Kirshblum SC and O'Connor KC. Levels of spinal cord injury and predictors of neurologic recovery. In: Kraft GH and Hammond MC, eds. Physical Medicine and Rehabilitation Clinics of North America, Topics in Spinal Cord Injury Medicine. Philadelphia: W.B. Saunders Co., 2000; 11(1):1-28.
  7. Maynard FM, Bracken MB, Creasey G, Ditunno JF, et al. The International standards for neurological and functional classification of spinal cord injury. Spinal Cord 1997; 35:266-274.
  8. Nesathurai S and Gwardjan A. Clinical and Functional Evaluation. In: Nesathurai, S, ed. The Rehabilitation of People with Spinal Cord Injury. 2nd Ed. Malden, MA: Blackwell Science, Inc., 2000; 31-36.
  9. Nesathurai S and Gwardjan A. Functional outcomes by level of injury. In: Nesathurai, S, ed. The Rehabilitation of People with Spinal Cord Injury. 2nd Ed. Malden, MA: Blackwell Science, Inc., 2000; 37-38.
  10. Spinal Cord Injury: Facts and Figures at a Glance. January 2000. National Spinal Cord Injury Statistical Center. Birmingham, AL. [Available at www.spinalcord.uab.edu/show.asp?durki=21446 ].
  11. Stass W, Formal C, Freedman M, Fried G and Read M. Spinal Cord Injury and SCI Medicine. In: DeLisa, JA. Rehabilitation Medicine: Principles and Practice. 3rd Ed. Philadelphia: Lippincott Co, 1998.
  12. Stover, SL, Whiteneck, GG, DeLisa, GG, eds. Spinal Cord Injury, Clinical Outcomes from the Model Systems. Gaithersburg, MD. Aspen Publishers; 1995.

Organizations

  • American Spinal Injury Association (ASIA)
    www.asia-spinalinjury.org
    345 E Superior St, Rm 1436n Chicago, IL 60611
    312-238-1242
  • Paralyzed Veterans of America (PVA)
    www.pva.org
    801 18th St. NW, Washington, DC 20006
    800-424-8200 or Email: info@pva.org
  • National Spinal Cord Injury Statistical Center
    UAB-Spain Rehabilitation Center, Rm 544
    619 19th St. S, SRC 544., Birmingham, AL 35249-7330
    205-934-5359 or Email: nscisc@uab.edu

SCI NIDRR
Published by:
Medical RRTC on Secondary Conditions of SCI
UAB Spain Rehabilitation Center
619 19th Street South - SRC 529
Birmingham, AL 35249-7330
(205) 934-3283 or (205) 934-4642 (TTD only)

Revised: June, 2000
Developed by: Linda Lindsey, MEd and Phil Klebine, MA
Project Director: Amie B Jackson, MD, Project Director
© 2000 Board of Trustees of the University of Alabama
The University of Alabama at Birmingham provides equal opportunity in education and employment. This publication is supported by grant H133B980016 from the National Institute of Disability and Rehabilitation Research, Office of Special Education and Rehabilitative Services, U.S. Department of Education, Washington, DC. Opinions expressed in this document are not necessarily those of the granting agency.

 
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